Mood Swings in Women 45-49 years

Perimenopausal mood swings involve rapid emotional changes - from calm to angry or sad within minutes. Unlike PMS, these are more frequent and unpredictable. Cause: fluctuating estrogen disrupts serotonin and dopamine, the two key mood-regulation neurotransmitters. At 45-49, many women are in active perimenopause with the most severe symptoms because estrogen fluctuation peaks here. This is also when most Malaysian women consider serious clinical treatment. The optimal hormone therapy starting window is here - potential benefits and risks should be reviewed individually for each suitable woman. Starting resistance training now is critical. Mood swings at 45-49 are often severe and can affect family relationships. Omega-3 EPA/DHA + ashwagandha are herbal options some women ask about. For severe cases, low-dose certain antidepressants may help selected patients after clinician review.